Vitamin B12 Deficiency: Cardiologist Explains Fatigue Link and Dietary Sources

Friday - 27/06/2025 18:30
Persistent fatigue could signal a vitamin B12 deficiency, a concern affecting nearly half of the Indian population. Cardiologist Dr. Alok Chopra highlights B12's crucial role in energy production, DNA synthesis, and nervous system function. Found in fish, poultry, and fortified foods, B12 deficiency can lead to fatigue, pale skin, and neurological issues. While supplements and fortified foods can help, Dr.

Experiencing persistent fatigue? It's a common complaint, but it shouldn't be ignored. Feeling drained, even after sufficient rest, could indicate an underlying issue, and one potential culprit is a vitamin B12 deficiency. This essential nutrient plays a critical role in numerous bodily functions.

Foods rich in Vitamin B12

According to a 2019 study, approximately 47% of the Indian population suffers from a vitamin B12 deficiency. Dr. Alok Chopra, a leading cardiologist and functional medicine expert, sheds light on the importance of vitamin B12, its natural sources, and the potential risks associated with its deficiency, particularly among vegetarians.

What is Vitamin B12?

Vitamin B12 is a water-soluble nutrient vital for overall health. Dr. Chopra emphasizes its crucial role in metabolism, digestion, and maintaining overall well-being. It's naturally found in certain foods, available as a dietary supplement, and also prescribed as medication.

Sources of Vitamin B12

Vitamin B12 is naturally present in animal products such as:

  • Fish
  • Poultry
  • Eggs
  • Milk

However, it is largely absent from plant-based foods unless they are fortified. Dr. Chopra notes that vegetarians often struggle to obtain sufficient B12 from their diets alone.

Supplements for Vitamin B12

While plant-based foods typically lack B12, fortified options like nutritional yeast and certain cereals can provide a reliable source. Dr. Chopra suggests vegetarians consider supplements or B12-fortified products to meet their daily requirements.

Functions of Vitamin B12

Vitamin B12 is integral to several key bodily functions, including:

  • Red Blood Cell Production: It's vital for producing healthy red blood cells and preventing megaloblastic anemia.
  • DNA Synthesis: It plays a crucial role in the replication and maintenance of DNA within cells.
  • Nervous System Support: Vitamin B12 maintains the health of nerve cells and ensures the proper functioning of the nervous system.
  • Energy Production: It aids in converting carbohydrates into glucose for energy.
  • Brain Health: Vitamin B12 boosts memory, focus, and overall cognitive function, while reducing the risk of neurodegenerative diseases.
  • Heart Health: It helps regulate homocysteine levels in the blood, lowering the risk of cardiovascular disease.
  • Mood Regulation: Contributes to a balanced mood.
  • Bone Health: Supports bone density and strength.
  • Skin, Hair, and Nail Health: Promotes healthy skin, hair, and nails.
  • Immune System Support: Strengthens the immune system.

Signs of Vitamin B12 Deficiency

Despite its importance, vitamin B12 deficiency is common. Symptoms can include:

  • Fatigue
  • Pale or yellow skin
  • Headaches
  • Depressive symptoms
  • Gastrointestinal issues
  • Difficulty focusing
  • Glossitis and mouth ulcers
  • Weight loss
  • General feeling of being unwell
Symptoms of Vitamin B12 deficiency

Dr. Chopra advises that B12 deficiency can be addressed through proper nutrition, intramuscular injections, or oral B12 therapy.

He also cautions against excessive vitamin B12 intake, which can lead to adverse effects such as diarrhea, itching, rashes, headache, dizziness, nausea, and heart failure. Individuals with optic neuropathy, polycythemia, gout, iron or folate deficiency, or low potassium levels should consult a doctor before taking B12 supplements.

Interactions with Other Nutrients

Dr. Chopra advises against taking vitamin B12 supplements concurrently with vitamin D. He explains that vitamin D, being fat-soluble, is better absorbed with food, while B12, being water-soluble, is best taken on an empty stomach. The same principle applies to vitamin C.

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